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A meta-analysis of five trials comparing this regimenwith six to 12 months of isoniazid monotherapy suggested no difference in safety or effectiveness failure rates of 4.

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Isoniazid is generally well tolerated at recommended dosesSystemic or cutaneous hypersensitivity reactions occasionally occur during the first weeks of treatment.

Isoniazid is also used as preventative treatment against tuberculosis in those exposed to high-risk environments.

Use caution with the foods listed belowThey can interact with isoniazid and cause a reaction that includes a severe headachelarge pupilsneck stiffnessnauseavomitingdiarrheaflushingsweatingitchingirregular heartbeatsand chest painA reaction will not necessarily occurbut eat these foods with caution until you know if you will react to themCall your doctor immediately if you experience any of these symptoms.

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